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Prediction desk

Louisville Cardinals

NCAA Football · Football

All high-rated: when we backed LOU

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LOU top-tier record

No LOU pick has been designated Covered Select yet.

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Upcoming LOU games

NCAA FootballSat, 3:15 PM EDTPending

Stanford Cardinal vs. Louisville Cardinals

Spread

LOU -22.5

Total 59.5

Pending pick

19–41 · STAN +22.5

Locked Oct 31, 2026 · 1:04 PM EDT — spreads can move after this.

low confidence

LiveSTAN 24 — LOU 52End of 4th

Not coveringOn the numberCovering

Short by 5.5 points against STAN +22.5.

Score as of Oct 31, 6:52 PM EDT

NCAA FootballSat, 12:00 AM EST

Louisville Cardinals vs. North Carolina Tar Heels

Spread

LOU -3

Total 59.5

Preview

30–28 · UNC +2.5

Locked Nov 4, 2026 · 6:09 PM EST — spreads can move after this.

low confidence

LOU results — graded picks

NCAA FootballFinal

Florida State Seminoles vs. Louisville Cardinals

Final FSU 20 — LOU 44

Spread

LOU -4

Total 60.5

Graded pick

29–31 · No pick

NCAA FootballFinal

Louisville Cardinals vs. NC State Wolfpack

Final LOU 28 — NCSU 31

Spread

LOU -5.5

Total 56.5

Graded pick

31–26 · No pick

NCAA FootballFinal

Wake Forest Demon Deacons vs. Louisville Cardinals

Final WAKE 30 — LOU 27

Spread

LOU -13.5

Total 57.5

Graded pick

27–26 · No pick

NCAA FootballFinal

SMU Mustangs vs. Louisville Cardinals

Final SMU 31 — LOU 41

Spread

LOU -3

Total 57.5

Graded pick

27–30 · No pick

NCAA FootballFinalMissed

Villanova Wildcats vs. Louisville Cardinals

Final VILL 13 — LOU 59

Spread

LOU -38.5

Total 56.5

Graded pick

10–47 · VILL +38.5

low confidence

LOU previews & recaps

Sat, 12:00 AM EST · Preview

Preview: Louisville Cardinals at North Carolina Tar Heels

projected 30–28 · UNC +2.5

Sat, 3:15 PM EDT · Preview

Preview: Stanford Cardinal at Louisville Cardinals projection

projected 19–41 · STAN +22.5

Final · Preview

Preview: Florida State Seminoles at Louisville Cardinals projection

Final FSU 20 — LOU 44 · projected 29–31 · No pick

Final · Preview

Preview: Louisville Cardinals at NC State Wolfpack projection

Final LOU 28 — NCSU 31 · projected 31–26 · No pick

Final · Preview

Preview: Wake Forest Demon Deacons at Louisville Cardinals projection

Final WAKE 30 — LOU 27 · projected 27–26 · No pick

Final · Preview

Preview: SMU Mustangs at Louisville Cardinals projection

Final SMU 31 — LOU 41 · projected 27–30 · No pick

Final · Recap

Post-game: Louisville Dominates Villanova to Cover Big Spread

Final VILL 13 — LOU 59 · projected 10–47 · VILL +38.5

Final · Recap

Post-game: Ole Miss Holds Off Louisville in High-Scoring Shootout

Final LOU 38 — MISS 41 · projected 26–28 · MISS PK